Anti-Calmodulin/CALM 1/2/3 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.
Synonyms
CALM1; CALM; CAM; CAM1; Calmodulin-1; CALM2; CAM2; CAMB; Calmodulin-2; CALM3; CALML2; CAM3; CAMC; CAMIII; Calmodulin-3
Gene Name
CALM1/2/3
Gene ID
801805808
UniProt
P0DP23, P0DP24, P0DP25
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Calmodulin/CALM 1/2/3.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Abzhanov, A., Kuo, W. P., Hartmann, C., Grant, B. R., Grant, P. R., Tabin, C. J. The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches. Nature 442: 563-567, 2006. 2. Abzhanov, A., Protas, M., Grant, R. B., Grant, P. R., Tabin, C. J. Bmp4 and morphological variation of beaks in Darwin's finches. Science 305: 1462-1465, 2004. 3. Berchtold, M. W., Egli, R., Rhyner, J. A., Hameister, H., Strehler, E. E. Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3. Genomics 16: 461-465, 1993.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
17 kDa
Gene Name Synonym
Calmodulin 1/2/3
Protein Name
Calmodulin-1/2/3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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