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Anti-Calmodulin/CALM 1/2/3 Antibody Picoband® Biotin Conjugated

Product Specifications

Background

This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.

Synonyms

CALM1; CALM; CAM; CAM1; Calmodulin-1; CALM2; CAM2; CAMB; Calmodulin-2; CALM3; CALML2; CAM3; CAMC; CAMIII; Calmodulin-3

Gene Name

CALM1/2/3

Gene ID

801805808

UniProt

P0DP23, P0DP24, P0DP25

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Calmodulin/CALM 1/2/3.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Abzhanov, A., Kuo, W. P., Hartmann, C., Grant, B. R., Grant, P. R., Tabin, C. J. The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches. Nature 442: 563-567, 2006. 2. Abzhanov, A., Protas, M., Grant, R. B., Grant, P. R., Tabin, C. J. Bmp4 and morphological variation of beaks in Darwin's finches. Science 305: 1462-1465, 2004. 3. Berchtold, M. W., Egli, R., Rhyner, J. A., Hameister, H., Strehler, E. E. Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3. Genomics 16: 461-465, 1993.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

17 kDa

Gene Name Synonym

Calmodulin 1/2/3

Protein Name

Calmodulin-1/2/3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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