Anti-EIF4H Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
Synonyms
EIF4H; KIAA0038; WBSCR1; WSCR1; Eukaryotic translation initiation factor 4H; eIF-4H; Williams-Beuren syndrome chromosomal region 1 protein
Gene Name
EIF4H
Gene ID
7458
UniProt
Q15056
Host
Rabbit
Reactivity
Human, Monkey
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human EIF4H recombinant protein (Position: M1-E248) . Human EIF4Hshares 98.8% and 98% amino acid (aa) sequence identity with mouse and rat EIF4H, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Osborne, L. R., Martindale, D., Scherer, S. W., Shi, X.-M., Huizenga, J., Heng, H. H. Q., Costa, T., Pober, B., Lew, L., Brinkman, J., Rommens, J., Koop, B., Tsui, L.-C. Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients. Genomics 36: 328-336, 1996. 2. Richter-Cook, N. J., Dever, T. E., Hensold, J. O., Merrick, W. C. Purification and characterization of a new eukaryotic protein translation factor: eukaryotic initiation factor 4H. J. Biol. Chem. 273: 7579-7587, 1998.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
25 kDa
Applications Notes
6
Gene Name Synonym
Eukaryotic translation initiation factor 4H
Protein Name
Eukaryotic translation initiation factor 4H
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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