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Anti-EIF4H Antibody Picoband® Biotin Conjugated

Product Specifications

Background

This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

Synonyms

EIF4H; KIAA0038; WBSCR1; WSCR1; Eukaryotic translation initiation factor 4H; eIF-4H; Williams-Beuren syndrome chromosomal region 1 protein

Gene Name

EIF4H

Gene ID

7458

UniProt

Q15056

Host

Rabbit

Reactivity

Human, Monkey

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human EIF4H recombinant protein (Position: M1-E248) . Human EIF4Hshares 98.8% and 98% amino acid (aa) sequence identity with mouse and rat EIF4H, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Osborne, L. R., Martindale, D., Scherer, S. W., Shi, X.-M., Huizenga, J., Heng, H. H. Q., Costa, T., Pober, B., Lew, L., Brinkman, J., Rommens, J., Koop, B., Tsui, L.-C. Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients. Genomics 36: 328-336, 1996. 2. Richter-Cook, N. J., Dever, T. E., Hensold, J. O., Merrick, W. C. Purification and characterization of a new eukaryotic protein translation factor: eukaryotic initiation factor 4H. J. Biol. Chem. 273: 7579-7587, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

25 kDa

Gene Name Synonym

Eukaryotic translation initiation factor 4H

Protein Name

Eukaryotic translation initiation factor 4H

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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