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Anti-IFIT2 Antibody Picoband® HRP Conjugated

Product Specifications

Background

Enables RNA binding activity. Involved in antiviral innate immune response and positive regulation of apoptotic process. Located in endoplasmic reticulum.

Synonyms

IFIT2; CIG-42; G10P2; IFI54; ISG54; Interferon-induced protein with tetratricopeptide repeats 2; IFIT-2; ISG-54 K; Interferon-induced 54 kDa protein; IFI-54K; P54

Gene Name

IFIT2

Gene ID

3433

UniProt

P09913

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human IFIT2 recombinant protein (Position: N23-E458) . Human IFIT2 shares 62.2% amino acid (aa) sequence identity with mouse IFIT2.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Daffis, S., Szretter, K. J., Schriewer, J., Li, J., Youn, S., Errett, J., Lin, T.-Y., Schneller, S., Zust, R., Dong, H., Thiel, V., Sen, G. C., Fensterl, V., Klimstra, W. B., Pierson, T. C., Buller, R. M., Gale, M., Jr., Shi, P.-Y., Diamond, M. S. 2-prime-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature 468: 452-456, 2010. 2. Lafage, M., Clauss, I., Couez, D., Simonetti, J., Wathelet, M. G., Huez, G. The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24. Genomics 13: 458-460, 1992. 3. Wathelet, M. G., Szpirer, J., Nols, C. B., Clauss, I. M., De Wit, L., Islam, M. Q., Levan, G., Horisberger, M. A., Content, J., Szpirer, C., Huez, G. A. Cloning and chromosomal location of human genes inducible by type I interferon. Somat. Cell Molec. Genet. 14: 415-426, 1988.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

55 kDa

Gene Name Synonym

Interferon induced protein with tetratricopeptide repeats 2

Protein Name

Interferon-induced protein with tetratricopeptide repeats 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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