Anti-IFIT2 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables RNA binding activity. Involved in antiviral innate immune response and positive regulation of apoptotic process. Located in endoplasmic reticulum.
Synonyms
IFIT2; CIG-42; G10P2; IFI54; ISG54; Interferon-induced protein with tetratricopeptide repeats 2; IFIT-2; ISG-54 K; Interferon-induced 54 kDa protein; IFI-54K; P54
Gene Name
IFIT2
Gene ID
3433
UniProt
P09913
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human IFIT2 recombinant protein (Position: N23-E458) . Human IFIT2 shares 62.2% amino acid (aa) sequence identity with mouse IFIT2.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Daffis, S., Szretter, K. J., Schriewer, J., Li, J., Youn, S., Errett, J., Lin, T.-Y., Schneller, S., Zust, R., Dong, H., Thiel, V., Sen, G. C., Fensterl, V., Klimstra, W. B., Pierson, T. C., Buller, R. M., Gale, M., Jr., Shi, P.-Y., Diamond, M. S. 2-prime-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature 468: 452-456, 2010. 2. Lafage, M., Clauss, I., Couez, D., Simonetti, J., Wathelet, M. G., Huez, G. The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24. Genomics 13: 458-460, 1992. 3. Wathelet, M. G., Szpirer, J., Nols, C. B., Clauss, I. M., De Wit, L., Islam, M. Q., Levan, G., Horisberger, M. A., Content, J., Szpirer, C., Huez, G. A. Cloning and chromosomal location of human genes inducible by type I interferon. Somat. Cell Molec. Genet. 14: 415-426, 1988.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
55 kDa
Gene Name Synonym
Interferon induced protein with tetratricopeptide repeats 2
Protein Name
Interferon-induced protein with tetratricopeptide repeats 2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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