Anti-NEUROG1 Antibody Picoband® APC Conjugated

Enables E-box binding activity and protein homodimerization activity. Involved in several processes, including cochlea morphogenesis; cranial nerve development; and hard palate morphogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus.

NEUROG1; BHLHA6; NEUROD3; NGN; NGN1; Neurogenin-1; NGN-1; Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3

A synthetic peptide corresponding to a sequence at the N-terminus of human NEUROG1. Human NEUROG1 shares 93.8% amino acid (aa) sequence identity with both mouse and rat NEUROG1.

1. Dupont, J., Vieira, J. P., Tavares, A. L. T., Conceicao, C. R., Khan, S., Bertoli-Avella, A. M., Sousa, A. B. Adding evidence to the role of NEUROG1 in congenital cranial dysinnervation disorders. Clin. Genet. 99: 588-593, 2021. 2. Gowan, K., Helms, A. W., Hunsaker, T. L., Collisson, T., Ebert, P. J., Odom, R., Johnson, J. E. Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons. Neuron 31: 219-232, 2001. 3. Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N., Weintraub, H. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268: 836-844, 1995.