Anti-NDUFA10 Antibody Picoband®

The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome.

NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Complex I-42kD; CI-42kD; NADH-ubiquinone oxidoreductase 42 kDa subunit

E.coli-derived human NDUFA10 recombinant protein (Position: H85-R332) . Human NDUFA10shares 91.7% and 90.1% amino acid (aa) sequence identity with mouse and rat NDUFA10, respectively.

1. Amberger, J. S. Personal Communication. Baltimore, Md. 6/11/2008. 2. Baens, M., Chaffanet, M., Cassiman, J.-J., van den Berghe, H., Marynen, P. Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid. Genomics 16: 214-218, 1993. 3. Hoefs, S. J. G., van Spronsen, F. J., Lenssen, E. W. H., Nijtmans, L. G., Rodenburg, R. J., Smeitink, J. A. M., van den Heuvel, L. P. NDUFA10 mutations cause complex I deficiency in a patient with Leigh disease. Europ. J. Hum. Genet. 19: 270-274, 2011.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.