Anti-PYGM Antibody Picoband® HRP Conjugated
Product Specifications
Background
This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.
Synonyms
PYGM; Glycogen phosphorylase, muscle form; EC 2.4.1.1; Myophosphorylase
Gene Name
PYGM
Gene ID
5837
UniProt
P11217
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PYGM recombinant protein (Position: V390-R804) . Human PYGMshares 95.9% and 94.2% amino acid (aa) sequence identity with mouse and rat PYGM, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Andreu, A. L., Nogales-Gadea, G., Cassandrini, D., Arenas, J., Bruno, C. McArdle disease: molecular genetic update. Acta Myol. 26: 53-57, 2007. 2. Bartram, C., Edwards, R. H. T., Clague, J., Beynon, R. J. McArdle's disease: a nonsense mutation in exon 1 of the muscle glycogen phosphorylase gene explains some but not all cases. Hum. Molec. Genet. 2: 1291-1293, 1993. 3. Bruno, C., Lofberg, M., Tamburino, L., Jankala, H., Hadjigeorgiou, G. M., Andreu, A. L., Shanske, S., Somer, H., DiMauro, S. Molecular characterization of McArdle's disease in two large Finnish families. J. Neurol. Sci. 165: 121-125, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
97 kDa
Gene Name Synonym
Glycogen phosphorylase, muscle associated
Protein Name
Glycogen phosphorylase, muscle form
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15191991 1 Vial
Lentiviral mouse Olfm1 shRNA (UAS) - Lentiviral mouse Olfm1 shRNA (UAS, iRFP) (100)
Ask
View Details 
