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Anti-HK3 Antibody Picoband® HRP Conjugated

Product Specifications

Background

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.

Synonyms

HK3; Hexokinase-3; EC 2.7.1.1; Hexokinase type III; HK III; Hexokinase-C

Gene Name

HK3

Gene ID

3101

UniProt

P52790

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human HK3 recombinant protein (Position: M1-K789) . Human HK3shares 84.7% and 84.8% amino acid (aa) sequence identity with mouse and rat HK3, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Colosimo, A., Calabrese, G., Gennarelli, M., Ruzzo, A. M., Sangiuolo, F., Magnani, M., Palka, G., Novelli, G., Dallapiccola, B. Assignment of the hexokinase type 3 gene (HK3) to human chromosome band 5q35.3 by somatic cell hybrids and in situ hybridization. Cytogenet. Cell Genet. 74: 187-188, 1996. 2. Furuta, H., Nishi, S., Le Beau, M. M., Fernald, A. A., Yano, H., Bell, G. I. Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. Genomics 36: 206-209, 1996. 3. Harris, H., Hopkinson, D. A. Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphism. Ann. Hum. Genet. 36: 9-20, 1972.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

99 kDa

Gene Name Synonym

Hexokinase 3

Protein Name

Hexokinase-3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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