Anti-HK3 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.
Synonyms
HK3; Hexokinase-3; EC 2.7.1.1; Hexokinase type III; HK III; Hexokinase-C
Gene Name
HK3
Gene ID
3101
UniProt
P52790
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human HK3 recombinant protein (Position: M1-K789) . Human HK3shares 84.7% and 84.8% amino acid (aa) sequence identity with mouse and rat HK3, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Colosimo, A., Calabrese, G., Gennarelli, M., Ruzzo, A. M., Sangiuolo, F., Magnani, M., Palka, G., Novelli, G., Dallapiccola, B. Assignment of the hexokinase type 3 gene (HK3) to human chromosome band 5q35.3 by somatic cell hybrids and in situ hybridization. Cytogenet. Cell Genet. 74: 187-188, 1996. 2. Furuta, H., Nishi, S., Le Beau, M. M., Fernald, A. A., Yano, H., Bell, G. I. Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization. Genomics 36: 206-209, 1996. 3. Harris, H., Hopkinson, D. A. Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphism. Ann. Hum. Genet. 36: 9-20, 1972.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
99 kDa
Gene Name Synonym
Hexokinase 3
Protein Name
Hexokinase-3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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