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Anti-Hephaestin/HEPH Antibody Picoband®

Boster Bio Anti-Hephaestin/HEPH Antibody Picoband® catalog # A05316-1. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Enables ferroxidase activity. Involved in intestinal iron absorption; multicellular organismal-level iron ion homeostasis; and positive regulation of iron export across plasma membrane. Acts upstream of or within erythrocyte differentiation. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in basolateral plasma membrane. Orthologous to human HEPH (hephaestin) .

Synonyms

Heph; Kiaa0698; Hephaestin; EC 1.-.-.-

Gene Name

HEPH

Gene ID

15203

UniProt

Q9Z0Z4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human Hephaestin/HEPH recombinant protein (Position: E348-Q1157) . Mouse Hephaestin/HEPHshares 85.6% and 96.2% amino acid (aa) sequence identity with human and rat Hephaestin/HEPH, respectively.

Clonality

Polyclonal

Applications

WB, IHC, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Anderson, G. J., Murphy, T. L., Cowley, L., Evans, B. A., Halliday, J. W., McLaren, G. D. Mapping the gene for sex-linked anemia: an inherited defect of intestinal iron absorption in the mouse. Genomics 48: 34-39, 1998. 2. Bannerman, R. M. Genetic defects of iron transport. Fed. Proc. 35: 2281-2285, 1976. 3. Edwards, J. A., Hoke, J. E., Mattioli, M., Reichlin, M. Ferritin distribution and synthesis in sex-linked anemia. J. Lab. Clin. Med. 90: 68-76, 1977.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

130 kDa

Observed Molecular Weight

130 kDa

Applications Notes

6

Gene Name Synonym

Hephaestin

Protein Name

Hephaestin

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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