Anti-Hephaestin/HEPH Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables ferroxidase activity. Involved in intestinal iron absorption; multicellular organismal-level iron ion homeostasis; and positive regulation of iron export across plasma membrane. Acts upstream of or within erythrocyte differentiation. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in basolateral plasma membrane. Orthologous to human HEPH (hephaestin) .
Synonyms
Heph; Kiaa0698; Hephaestin; EC 1.-.-.-
Gene Name
HEPH
Gene ID
15203
UniProt
Q9Z0Z4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human Hephaestin/HEPH recombinant protein (Position: E348-Q1157) . Mouse Hephaestin/HEPHshares 85.6% and 96.2% amino acid (aa) sequence identity with human and rat Hephaestin/HEPH, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Anderson, G. J., Murphy, T. L., Cowley, L., Evans, B. A., Halliday, J. W., McLaren, G. D. Mapping the gene for sex-linked anemia: an inherited defect of intestinal iron absorption in the mouse. Genomics 48: 34-39, 1998. 2. Bannerman, R. M. Genetic defects of iron transport. Fed. Proc. 35: 2281-2285, 1976. 3. Edwards, J. A., Hoke, J. E., Mattioli, M., Reichlin, M. Ferritin distribution and synthesis in sex-linked anemia. J. Lab. Clin. Med. 90: 68-76, 1977.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
130 kDa
Gene Name Synonym
Hephaestin
Protein Name
Hephaestin
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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