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Anti-H6PD Antibody Picoband® HRP Conjugated

Product Specifications

Background

There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.

Synonyms

H6PD; GDH; GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase; EC 1.1.1.47; Glucose-6-phosphate dehydrogenase; EC 1.1.1.363; 6-phosphogluconolactonase; 6PGL; EC 3.1.1.31]

Gene Name

H6PD

Gene ID

9563

UniProt

O95479

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human H6PD recombinant protein (Position: A69-N683) . Human H6PDshares 81.5% and 83.9% amino acid (aa) sequence identity with mouse and rat H6PD, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Beutler, E., Morrison, M. Localization and characteristics of hexose 6-phosphate dehydrogenase (glucose dehydrogenase) . J. Biol. Chem. 242: 5289-5293, 1967. 2. Biason-Lauber, A., Suter, S. L., Shackleton, C. H. L., Zachmann, M. Apparent cortisone reductase deficiency: a rare cause of hyperandrogenemia and hypercortisolism. Horm. Res. 53: 260-266, 2000. 3. Carritt, B., King, J., Welch, H. M. Gene order and localization of enzyme loci on the short arm of chromosome 1. Ann. Hum. Genet. 46: 329-335, 1982.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

89 kDa

Gene Name Synonym

Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase

Protein Name

GDH/6PGL endoplasmic bifunctional protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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