Anti-MEOX2 Antibody Picoband® HRP Conjugated

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease.

A synthetic peptide corresponding to a sequence at the C-terminus of human MEOX2. Human MEOX2 shares 100% amino acid (aa) sequence identity with both mouse and rat MEOX2.

1. Candia, A. F., Hu, J., Crosby, J., Lalley, P. A., Noden, D., Nadeau, J. H., Wright, C. V. E. Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development 116: 1123-1136, 1992. 2. Cao, G., Huang, B., Liu, Z., Zhang, J., Xu, H., Xia, W., Li, J., Li, S., Chen, L., Ding, H., Zhao, Q., Fan, M., Shen, B., Shao, N. Intronic miR-301 feedback regulates its host gene, ska2, in A549 cells by targeting MEOX2 to affect ERK/CREB pathways. Biochem. Biophys. Res. Commun. 396: 978-982, 2010. 3. Chen, Y., Gorski, D. H. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 111: 1217-1226, 2008.