Anti-MC5R Antibody Picoband® Biotin Conjugated

Predicted to enable hormone binding activity and melanocortin receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to be active in cytoplasm and plasma membrane. Is expressed in skin. Orthologous to human MC5R (melanocortin 5 receptor) .

A synthetic peptide corresponding to a sequence in the middle region of mouse MC5R. Mouse MC5R shares 95.5% amino acid (aa) sequence identity with both human and rat MC5R.

1. Chen, W., Kelly, M. A., Opitz-Araya, X., Thomas, R. E., Low, M. J., Cone, R. D. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91: 789-798, 1997. 2. Chowdhary, B. P., Gustavsson, I., Wikberg, J. E. S., Chhajlani, V. Localization of the human melanocortin-5 receptor gene (MC5R) to chromosome band 18p11.2 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 68: 79-81, 1995. 3. Gantz, I., Shimoto, Y., Konda, Y., Miwa, H., Dickinson, C. J., Yamada, T. Molecular cloning, expression, and characterization of a fifth melanocortin receptor. Biochem. Biophys. Res. Commun. 200: 1214-1220, 1994.