Anti-USP14 Antibody Picoband® Fluoro550 Conjugated
Product Specifications
Background
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms
USP14; TGT; Ubiquitin carboxyl-terminal hydrolase 14; EC 3.4.19.12; Deubiquitinating enzyme 14; Ubiquitin thioesterase 14; Ubiquitin-specific-processing protease 14
Gene Name
USP14
Gene ID
9097
UniProt
P54578
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human USP14 recombinant protein (Position: D23-Q427) . Human USP14 shares 96.3% amino acid (aa) sequence identity with mouse USP14.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Dennehey, B. K., Gutches, D. G., McConkey, E. H., Krauter, K. S. Inversion, duplication, and changes in gene context are associated with human chromosome 18 evolution. Genomics 83: 493-501, 2004. 2. Deshpande, K. L., Seubert, P. H., Tillman, D. M., Farkas, W. R., Katze, J. R. Cloning and characterization of cDNA encoding the rabbit tRNA-guanine transglycosylase 60-kilodalton subunit. Arch. Biochem. Biophys. 326: 1-7, 1996. 3. Gross, M. B. Personal Communication. Baltimore, Md. 7/13/2015.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A03042-3-Fluoro550
Calculated Molecular Weight
56 kDa
Applications Notes
6
Gene Name Synonym
Ubiquitin specific peptidase 14
Protein Name
Ubiquitin carboxyl-terminal hydrolase 14
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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