Anti-CLTA Antibody Picoband® HRP Conjugated
Product Specifications
Background
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.
Synonyms
CLTA; Clathrin light chain A; Lca
Gene Name
CLTA
Gene ID
1211
UniProt
P09496
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CLTA. Human CLTA shares 100% amino acid (aa) sequence identity with mouse CLTA.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Brodsky, F. M., Galloway, C. J., Blank, G. S., Jackson, A. P., Seow, H.-F., Drickamer, K., Parham, P. Localization of clathrin light-chain sequences mediating heavy-chain binding and coated vesicle diversity. Nature 326: 203-205, 1987. 2. Deborde, S., Perret, E., Gravotta, D., Deora, A., Salvarezza, S., Schreiner, R., Rodriguez-Boulan, E. Clathrin is a key regulator of basolateral polarity. Nature 452: 719-723, 2008. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/2/2011.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
27 kDa
Gene Name Synonym
Clathrin light chain A
Protein Name
Clathrin light chain A
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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