Anti-Zebrafish LZIC Antibody

LZIC is closely related to ICAT, a physiological inhibitor ofthe Wnt pathway that interacts physically and functionally withβ-catenin to prevent the transcription ofWnt target genes. LZIC'sICAT-homologousregion is highly similarto ICAT with particular conservation ofresiduesthat are used by ICAT forβ-catenin-binding. LZIC does not interactwithβ-catenin in vitro orin vivo. LZIC is a protein conserved in vertebrates, isrequired for neuronal survival.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.