Anti-Zebrafish ATG5 Antibody Picoband®
Boster Bio Anti-Zebrafish ATG5 Antibody Picoband® catalog # AZF1RDC0. Tested in IHC applications. This antibody reacts with Zebrafish.
Product Specifications
Background
Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is also known as APG5 or ASP, and this gene is mapped to 6q21. It is found that knockdown of ATG5 in hepatocytes increased triglyceride levels with oleate or a second endogenous stimulus for triglyceride formation. These hepatocytes with ATG5 knockdown also had increased lipid droplet number and size. ATG5 is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
Gene Name
ATG5
Gene ID
494180
UniProt
F1RDC0
Host
Rabbit
Reactivity
Zebrafish
Immunogen
E.coli-derived zebrafish ATG5 recombinant protein (Position: S118-L155) .
Clonality
Polyclonal
Applications
IHC
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Lyophilized
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Storage Conditions
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Isotype
Rabbit IgG
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
