Recombinant Mouse LIF Protein

LIF (leukemia inhibitory factor) is a widely expressed pleiotropic member of the IL-6 family of cytokines. The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Specifications

Gene Name

LIF

Gene ID

3976

UniProt

P15018

Reactivity

Mouse

Source

E. coli Ser24-Phe203

Purification

>95%, by SDS-PAGE quantitative densitometry by Coomassie? Blue Staining.

Endotoxin

Less than 1 EU/μg of LIF as determined by LAL method.

Form

Lyophilized

Storage Conditions

Lyophilized recombinant Mouse Leukemia Inhibitory Factor remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmLIF remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Product Datasheet

https://www.bosterbio.com/media/pdf/R01400-1_DS.pdf

Product MSDS

https://www.bosterbio.com/msds?sku=R01400-1

Calculated Molecular Weight

19.8KD

AA Sequence

SPLPI TPVNA TCAIR HPCHG NLMNQ IKNQL AQLNG SANAL FISYY TAQGE PFPNN VEKLC APNMT DFPSF HGNGT EKTKL VELYR MVAYL SASLT NITRD QKVLN PTAVS LQVKL NATID VMRGL LSNVL CRLCN KYRVG HVDVP PVPDH SDKEA FQRKK LGCQL LGTYK QVISV VVQAF

Reconstitute in ddH2O at 100 μg/mL.