DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis[1][2].

Product Specifications

CAS Number

[110764-79-9]

Product Name Alternative

2'-O-Me-U Phosphoramidite

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-2-o-methyl-ru-phosphoramidite.html

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C(NC(C=C5)=O)=O)O4

Molecular Formula

C40H49N4O9P

Molecular Weight

760.81

Precautions

H315, H319, H335

References & Citations

[1]Stump MD, et al. The use of modified primers to eliminate cycle sequencing artifacts. Nucleic Acids Res. 1999 Dec 1;27 (23) :4642-8.|[2]Takahashi M, et al. Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability. Nucleic Acids Res. 2009 Mar;37 (4) :1353-62.