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Anti-Fruit fly Spire Antibody Fluoro647 Conjugated

Product Specifications

Gene Name

Spir

Gene ID

45931

UniProt

Q9U1K1

Host

Rabbit

Reactivity

Fruit fly

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.

Applications

Flow Cytometry

Field of Research

Axonal Guidance Proteins, Growth and Development, Neural Signal Transduction, Neurology Process, Neuroscience

Purification

Immunogen affinity purified.

Concentration

500 μg/ml

Form

Liquid

Function

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity) . SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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