Anti-Human RBM45 Antibody Fluoro550 Conjugated

Product Specifications

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

E.coli-derived human RBM45 recombinant protein (Position: A2-R215+Q370-Y476) .

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.

Applications

Flow Cytometry

Field of Research

Axonal Guidance Proteins, Growth and Development, Neural Signal Transduction, Neurology Process, Neuroscience

Purification

Immunogen affinity purified.

Concentration

500 μg/ml

Form

Liquid

Function

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity) . SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.