Anti-Zebrafish Hand2 Antibody Fluoro488 Conjugated
Product Specifications
Gene Name
Hand2
UniProt
P57102
Host
Rabbit
Reactivity
Zebrafish
Clonality
Polyclonal
Tissue Specificity
Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.
Field of Research
Axonal Guidance Proteins, Growth and Development, Neural Signal Transduction, Neurology Process, Neuroscience
Purification
Immunogen affinity purified.
Concentration
500μg/ml
Form
Liquid
Function
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity) . SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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