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Anti-SCIN Rabbit Monoclonal Antibody

Boster Bio Anti-SCIN Rabbit Monoclonal Antibody catalog # M07463. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Trophoblast glycoprotein;5T4 oncofetal antigen;5T4 oncofetal trophoblast glycoprotein;5T4 oncotrophoblast glycoprotein; M6P1; Wnt-activated inhibitory factor 1; WAIF1; TPBG;5T4

Gene Name

SCIN

Gene ID

85477

UniProt

Q9Y6U3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SCIN

Clonality

Monoclonal

Clone

Clone: 27S73

Tissue Specificity

Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Applications

WB, IHC

Field of Research

Cancer, Developmental Biology, Lineage Markers, Lineage Specification, Stem Cells, Tumor Immunology, Tumor-Associated Antigens

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May function as an inhibitor of Wnt/beta-catenin signaling by inly interacting with LRP6 and blocking Wnt3a- dependent LRP6 internalization. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

80 kDa

Observed Molecular Weight

80 kDa

Gene Name Synonym

Trophoblast glycoprotein

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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