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Anti-CaMKII Rabbit Monoclonal Antibody

Boster Bio Anti-CaMKII Rabbit Monoclonal Antibody catalog # M03241-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha;2.7.11.17 ; CAMK2A; CAMKA, KIAA0968

Gene Name

CAMK2A/B/D/G

Gene ID

815

UniProt

Q9UQM7/Q13554/Q13555/Q13557

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human CaMKII

Clonality

Monoclonal

Clone

Clone: 27C04

Tissue Specificity

Expressed in brain in the thalamus, in fetal and adult lung and in placenta. .

Applications

WB, IHC, Flow Cytometry

Field of Research

Calcium Signaling, Calmodulin Pathway, Cardiovascular, Hypertrophy, Neuroscience, Neurotransmission, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) . Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378) . Activates FOXO3 transcriptional activity (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54088 MW

Observed Molecular Weight

50-70 kDa

Gene Name Synonym

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Subcellular Location

Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse . Postsynaptic lipid rafts. .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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