Anti-Human IgG1 Rabbit Monoclonal Antibody
Boster Bio Anti-Human IgG1 Rabbit Monoclonal Antibody catalog # M04575-6. Tested in WB application. This antibody reacts with Human.
Product Specifications
Synonyms
Ig gamma-1 chain C region; IGHG1
Gene Name
IGHG1
Gene ID
3500
UniProt
P01857
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human IgG1
Clonality
Monoclonal
Clone
Clone: 27I03
Tissue Specificity
According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.
Applications
WB
Field of Research
Immunoglobulins, Immunology
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
36106 MW
Observed Molecular Weight
52 kDa
Gene Name Synonym
Ig gamma-1 chain C region
Subcellular Location
Secreted.
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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