Anti-CTNNA3 Rabbit Monoclonal Antibody
Boster Bio Anti-CTNNA3 Rabbit Monoclonal Antibody catalog # M05039. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Polypyrimidine tract-binding protein 2; Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; PTB-like protein; PTBP2; NPTB, PTB, PTBLP
Gene Name
CTNNA3
Gene ID
29119
UniProt
Q9UI47
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human CTNNA3
Clonality
Monoclonal
Clone
Clone: 26C28
Tissue Specificity
Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues. .
Applications
WB, IHC, IP
Field of Research
Amino Acid Metabolism, Cancer, Cancer Metabolism, Carbohydrate Metabolism, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Carbohydrates, Pathways and Processes, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
57491 MW
Observed Molecular Weight
100 kDa
Gene Name Synonym
Polypyrimidine tract-binding protein 2
Subcellular Location
Nucleus .
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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