Anti-CXCL5 Rabbit Monoclonal Antibody

DNA-binding protein inhibitor ID-1; Class B basic helix-loop-helix protein 24; bHLHb24; Inhibitor of DNA binding 1; Inhibitor of differentiation 1; ID1; BHLHB24, ID

Angiogenesis, Cancer, Cancer Susceptibility, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Invasion/Microenvironment, Proto-Oncogenes, Signal Transduction, Transcription

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity) . .