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Anti-DBF4 Rabbit Monoclonal Antibody

Boster Bio Anti-DBF4 Rabbit Monoclonal Antibody catalog # M01348. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Hepcidin; Liver-expressed antimicrobial peptide 1; LEAP-1; Putative liver tumor regressor; PLTR; Hepcidin-25; Hepc25; Hepcidin-20; Hepc20; HAMP; HEPC, LEAP1; UNQ487/PRO1003

Gene Name

DBF4

Gene ID

10926

UniProt

Q9UBU7

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human DBF4

Clonality

Monoclonal

Clone

Clone: 24D74

Tissue Specificity

Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine. .

Applications

WB

Field of Research

Cancer, Cardiovascular, Cofactors, Vitamins/Minerals, Metabolism, Pathways and Processes, Serum Proteins, Signal Transduction, Vitamins/Minerals

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

9408 MW

Observed Molecular Weight

80 kDa

Gene Name Synonym

Hepcidin

Subcellular Location

Secreted.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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