Anti-PLTP Rabbit Monoclonal Antibody
Boster Bio Anti-PLTP Rabbit Monoclonal Antibody catalog # M02209. Tested in WB application. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Caspase-10; CASP-10;3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; Caspase-10 subunit p23/17; Caspase-10 subunit p12; CASP10; MCH4
Gene Name
PLTP
Gene ID
5360
UniProt
P55058
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthesized peptide derived from human PLTP
Clonality
Monoclonal
Clone
Clone: 24P68
Tissue Specificity
Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.
Applications
WB
Field of Research
Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Neuroscience, Sensory System, Transcription, Transcription Factors, Visual System
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
58951 MW
Observed Molecular Weight
80 kDa
Gene Name Synonym
Caspase-10
Subcellular Location
Cytoplasm. Nucleus. Cell membrane. Membrane, clathrin-coated pit . Cell projection, pseudopodium . Cytoplasmic vesicle. Translocates to the plasma membrane and colocalizes with antagonist-stimulated GPCRs. The monomeric form is predominantly located in the nucleus. The oligomeric form is located in the cytoplasm. Translocates to the nucleus upon stimulation of OPRD1 (By similarity) . .
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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