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Anti-FHIT Rabbit Monoclonal Antibody

Boster Bio Anti-FHIT Rabbit Monoclonal Antibody catalog # M01200-3. Tested in WB application. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106; VCAM1; L1CAM

Gene Name

FHIT

Gene ID

2272

UniProt

P49789

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human FHIT

Clonality

Monoclonal

Clone

Clone: 24F24

Tissue Specificity

Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.

Applications

WB

Field of Research

Atherosclerosis, Cancer, Cardiovascular, Cell Adhesion, Cell Adhesion Molecules, Cytoskeleton/ECM, Invasion/Microenvironment, Mesenchymal Stem Cells, Neural Signal Transduction, Neurology Process, Neuroscience, Signal Transduction, Stem Cells, Surface Molecules, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

81276 MW

Observed Molecular Weight

17 kDa

Gene Name Synonym

Vascular cell adhesion protein 1

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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