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Anti-Pannexin 1 Rabbit Monoclonal Antibody

Boster Bio Anti-Pannexin 1 Rabbit Monoclonal Antibody catalog # M00915. Tested in WB, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

CD59 glycoprotein;1F5 antigen;20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59; CD59; MIC11, MIN1, MIN2, MIN3, MSK21

Gene Name

PANX1

Gene ID

24145

UniProt

Q96RD7

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Pannexin 1

Clonality

Monoclonal

Clone

Clone: 24P11

Tissue Specificity

Detected in caudate, nucleus accumbens and in the olfactory tubercle. .

Applications

WB, IP

Field of Research

Atherosclerosis, Cardiovascular, Cell Type Markers, Complement, Hematopoietic Progenitors, Immunology, Innate Immunity, Protein Phosphorylation, Signal Transduction, Stem Cells, Surface Molecules, Tyrosine Kinases, Vascular Inflammation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14177 MW

Observed Molecular Weight

48 kDa

Gene Name Synonym

CD59 glycoprotein

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Soluble form found in a number of tissues.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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