Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ATGL / PNPLA2 Rabbit Monoclonal Antibody

Boster Bio Anti-ATGL / PNPLA2 Rabbit Monoclonal Antibody catalog # M01800. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP; HNRNPK; HNRPK

Gene Name

PNPLA2

Gene ID

57104

UniProt

Q96AD5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human ATGL / PNPLA2

Clonality

Monoclonal

Clone

Clone: 23P38

Tissue Specificity

Expressed in brain and lymphoblast.

Applications

WB

Field of Research

Chromatin Binding Proteins, DNA/RNA, DNA/RNA Binding, Epigenetics and Nuclear Signaling, RNA Processing, Splicing

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

One of the major pre-mRNA-binding proteins. Binds tenaciously to poly (C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly (C) single- stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity) . As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50976 MW

Observed Molecular Weight

55 kDa

Gene Name Synonym

Heterogeneous nuclear ribonucleoprotein K

Subcellular Location

Cytoplasm . Nucleus, nucleoplasm . Cell projection, podosome . Recruited to p53/TP53- responsive promoters, in the presence of functional p53/TP53 (PubMed:16360036) . In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear (PubMed:18775702) .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit
MBS7607140-01 48 Well

Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit

Ask
View Details
Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit
MBS7607140-02 96 Well

Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit

Ask
View Details
Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit
MBS7607140-03 5x 96 Well

Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit

Ask
View Details
Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit
MBS7607140-04 10x 96 Well

Rabbit Sod2 (Superoxide dismutase [Mn], mitochondrial) ELISA Kit

Ask
View Details
Capsid Antibody
MBS7164865 Inquire

Capsid Antibody

Ask
View Details
Recombinant Streptococcus pneumoniae Ribose-5-phosphate isomerase A (rpiA)
MBS1126975-01 0.02 mg (E-Coli)

Recombinant Streptococcus pneumoniae Ribose-5-phosphate isomerase A (rpiA)

Ask
View Details