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Anti-CRYAA Rabbit Monoclonal Antibody

Boster Bio Anti-CRYAA Rabbit Monoclonal Antibody catalog # M01900-4. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

M-phase inducer phosphatase 2;3.1.3.48; Dual specificity phosphatase Cdc25B; CDC25B; CDC25HU2

Gene Name

CRYAA

Gene ID

1409

UniProt

P02489

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human CRYAA

Clonality

Monoclonal

Clone

Clone: 23C19

Tissue Specificity

Widely expressed (PubMed:16044242) . Highly expressed in heart and skeletal muscle (PubMed:12802337) . Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337) . Weakly expressed in colon, thymus and small intestine (PubMed:12802337) . .

Applications

WB, ICC, IF

Field of Research

Cancer, Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling, Kinases/Phosphatases

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. ly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

64987 MW

Observed Molecular Weight

17 kDa, 20 kDa

Gene Name Synonym

M-phase inducer phosphatase 2

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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