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Anti-CCL19 Rabbit Monoclonal Antibody

Boster Bio Anti-CCL19 Rabbit Monoclonal Antibody catalog # M01605-2. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

C-C motif chemokine 19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19; CCL19; ELC, MIP3B, SCYA19

Gene Name

CCL19

Gene ID

6363

UniProt

Q99731

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CCL19

Clonality

Monoclonal

Clone

Clone: 23C03

Tissue Specificity

Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.

Applications

WB, Flow Cytometry

Field of Research

Chemokines, G Protein Signaling, Immunology, Innate Immunity, Macrophage/Inflammation, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

10993 MW

Observed Molecular Weight

11 kDa

Gene Name Synonym

C-C motif chemokine 19

Subcellular Location

Secreted.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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