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Anti-COPA Rabbit Monoclonal Antibody

Boster Bio Anti-COPA Rabbit Monoclonal Antibody catalog # M03987. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5;2.7.12.2; MAPK/ERK kinase 5; MEK 5; MAP2K5; MEK5, MKK5, PRKMK5

Gene Name

COPA

Gene ID

1314

UniProt

P53621

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human COPA

Clonality

Monoclonal

Clone

Clone: 22C64

Tissue Specificity

Expressed in many adult tissues. Abundant in heart and skeletal muscle.

Applications

WB, IHC

Field of Research

Cancer, Cardiogenesis, Cardiovascular, MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Serine/Threonine Kinases, Signal Transduction, Transcription Factors/Regulators

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50112 MW

Observed Molecular Weight

138 kDa

Gene Name Synonym

Dual specificity mitogen-activated protein kinase kinase 5

Subcellular Location

Cytoplasm, cytoskeleton . Cell projection, lamellipodium . At the interface between the lamellipodial actin meshwork and the membrane. .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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