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Anti-Timeless Rabbit Monoclonal Antibody

Boster Bio Anti-Timeless Rabbit Monoclonal Antibody catalog # M00831. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor; APOER; CD91; Low-density lipoprotein receptor-related protein 1 85 kDa subunit; LRP-85; Low-density lipoprotein receptor-related protein 1 515 kDa subunit; LRP-515; Low-density lipoprotein receptor-related protein 1 intracellular domain; LRPICD; LRP1; A2MR, APR

Gene Name

TIMELESS

Gene ID

8914

UniProt

Q9UNS1

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Timeless

Clonality

Monoclonal

Clone

Clone: 22T48

Tissue Specificity

Most abundant in liver, brain and lung.

Applications

WB, IHC, ICC, IF

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, Translation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

504606 MW

Observed Molecular Weight

150 kDa

Gene Name Synonym

Prolow-density lipoprotein receptor-related protein 1

Subcellular Location

Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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