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Anti-RING1 Rabbit Monoclonal Antibody

Boster Bio Anti-RING1 Rabbit Monoclonal Antibody catalog # M01824-1. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Midkine; MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MK1, NEGF2

Gene Name

RING1

Gene ID

6015

UniProt

Q06587

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human RING1

Clonality

Monoclonal

Clone

Clone: 22R33

Tissue Specificity

Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions. .

Applications

WB, IHC, ICC, IF

Field of Research

Growth and Development, Neurogenesis, Neurology Process, Neuroscience

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

15585 MW

Observed Molecular Weight

50 kDa

Gene Name Synonym

Midkine

Subcellular Location

Secreted.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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