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Anti-MAD3 Rabbit Monoclonal Antibody

Boster Bio Anti-MAD3 Rabbit Monoclonal Antibody catalog # M11285. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Histone H2B type 1-K; H2B K; HIRA-interacting protein 1; HIST1H2BK; H2BFT, HIRIP1

Gene Name

MXD3

Gene ID

83463

UniProt

Q9BW11

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human MAD3

Clonality

Monoclonal

Clone

Clone: 21M81

Tissue Specificity

Highly expressed in skeletal muscle, heart, liver and testis. .

Applications

WB, IHC, Flow Cytometry

Field of Research

Epigenetics and Nuclear Signaling, Histones, Unmodified

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

13890 MW

Observed Molecular Weight

28 kDa

Gene Name Synonym

Histone H2B type 1-K

Subcellular Location

Nucleus. Chromosome.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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