Anti-EBF1 Rabbit Monoclonal Antibody
Boster Bio Anti-EBF1 Rabbit Monoclonal Antibody catalog # M01341. Tested in WB application. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74; CD74; DHLAG
Gene Name
EBF1
Gene ID
1879
UniProt
Q9UH73
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human EBF1
Clonality
Monoclonal
Clone
Clone: 21E35
Tissue Specificity
Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level) . Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. .
Applications
WB
Field of Research
Adaptive Immunity, B Cells, Immunology
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and ing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
33516 MW
Observed Molecular Weight
64 kDa
Gene Name Synonym
HLA class II histocompatibility antigen gamma chain
Subcellular Location
Cell membrane ; Single-pass type II membrane protein . Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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