Anti-LIMK1 Rabbit Monoclonal Antibody
Boster Bio Anti-LIMK1 Rabbit Monoclonal Antibody catalog # M01323-1. Tested in WB application. This antibody reacts with Human Mouse Rat.
Product Specifications
Synonyms
Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP; NKX2-1 ; NKX2A, TITF1, TTF1
Gene Name
LIMK1
Gene ID
3984
UniProt
P53667
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human LIM Kinase 1
Clonality
Monoclonal
Clone
Clone: 20L63
Tissue Specificity
Thyroid and lung.
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling, Transcription
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
38596 MW
Observed Molecular Weight
38-42 kDa
Gene Name Synonym
Homeobox protein Nkx-2.1
Subcellular Location
Nucleus .
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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