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Anti-GDF15 Rabbit Monoclonal Antibody

Boster Bio Anti-GDF15 Rabbit Monoclonal Antibody catalog # M01583-1. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD325; CDH2; CDHN, NCAD

Gene Name

GDF15

Gene ID

9518

UniProt

Q99988

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human GDF15

Clonality

Monoclonal

Clone

Clone: 20G21

Tissue Specificity

Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. .

Applications

WB

Field of Research

Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

99809 MW

Observed Molecular Weight

48 kDa

Gene Name Synonym

Cadherin-2

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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