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Anti-Glutathione Synthetase Rabbit Monoclonal Antibody

Boster Bio Anti-Glutathione Synthetase Rabbit Monoclonal Antibody catalog # M00928-2. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

ADP-ribosylation factor 6; ARF6

Gene Name

GSS

Gene ID

2937

UniProt

P48637

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Glutathione Synthetase

Clonality

Monoclonal

Clone

Clone: 20G11

Tissue Specificity

Ubiquitous, with higher levels in heart, substantia nigra, and kidney. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

20082 MW

Observed Molecular Weight

52 kDa

Gene Name Synonym

ADP-ribosylation factor 6

Subcellular Location

Golgi apparatus. Cell membrane; Lipid- anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane ; Lipid-anchor . Cell projection, filopodium membrane; Lipid-anchor. Midbody . Cytoplasm . Cleavage furrow . Distributed throughout the cytoplasm during metaphase. Transiently detected at the ingressing cleavage furrow during mitotic cytokinesis. Recruited to the midbody at later stages of cytokinesis; this requires interaction with KIF23 (By similarity) . Recruited to the cell membrane in association with CYTH2 and ARL4C. Colocalizes with DAB2IP at the plasma membrane and endocytic vesicles. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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