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Anti-RanGAP1 Rabbit Monoclonal Antibody

Boster Bio Anti-RanGAP1 Rabbit Monoclonal Antibody catalog # M02771-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Nucleolysin TIA-1 isoform p40; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA-1; p40-TIA-1; TIA1

Gene Name

RANGAP1

Gene ID

5905

UniProt

P46060

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human RanGAP1

Clonality

Monoclonal

Clone

Clone: 19R47

Tissue Specificity

Widely expressed.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Adaptive Immunity, Apoptosis, Cancer, Cell Biology, Cell Death, DNA/RNA, Epigenetics and Nuclear Signaling, Immunology, Non-CD, Nucleus, RNA Processing, T Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs) . Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

42963 MW

Observed Molecular Weight

70 kDa, 90 kDa

Gene Name Synonym

Nucleolysin TIA-1 isoform p40

Subcellular Location

Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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