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Anti-NPHS2 Rabbit Monoclonal Antibody

Boster Bio Anti-NPHS2 Rabbit Monoclonal Antibody catalog # M01445-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Bactericidal permeability-increasing protein; BPI; CAP 57; BPI

Gene Name

NPHS2

Gene ID

7827

UniProt

Q9NP85

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NPHS2

Clonality

Monoclonal

Clone

Clone: 18N90

Tissue Specificity

Restricted to cells of the myeloid series.

Applications

WB, IHC

Field of Research

Cancer, Cell Biology, Cell Death, Immunology, Innate Immunity, Macrophage/Inflammation, Metabolism, Metabolism Processes, Pathways and Processes, T Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

53900 MW

Observed Molecular Weight

33 kDa

Gene Name Synonym

Bactericidal permeability-increasing protein

Subcellular Location

Secreted . Cytoplasmic granule membrane . Membrane-associated in polymorphonuclear Leukocytes (PMN) granules. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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