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Anti-HNF1 beta Rabbit Monoclonal Antibody

Boster Bio Anti-HNF1 beta Rabbit Monoclonal Antibody catalog # M01270-1. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Hepatocyte nuclear factor 1-beta; HNF-1-beta; HNF-1B; Homeoprotein LFB3; Transcription factor 2; TCF-2; Variant hepatic nuclear factor 1; vHNF1; HNF1B; TCF2

Gene Name

HNF1B

Gene ID

6928

UniProt

P35680

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human HNF1 beta

Clonality

Monoclonal

Clone

Clone: 18H22

Tissue Specificity

Preferentially expressed in melanomas. Some expression was found in dysplastic nevi. Not found in normal tissues nor in carcinomas. Normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth.

Applications

WB

Field of Research

Diabetes, Epigenetics and Nuclear Signaling, Metabolism, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

61324 MW

Observed Molecular Weight

70 kDa

Applications Notes

WB 1:500-1:2000

Gene Name Synonym

Hepatocyte nuclear factor 1-beta

Subcellular Location

Nucleus.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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