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Anti-MELK Rabbit Monoclonal Antibody

Boster Bio Anti-MELK Rabbit Monoclonal Antibody catalog # M04038-1. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE-1; Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor; LYVE1; CRSBP1, HAR, XLKD1; UNQ230/PRO263

Gene Name

MELK

Gene ID

9833

UniProt

Q14680

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MELK

Clonality

Monoclonal

Clone

Clone: 18M13

Tissue Specificity

Mainly expressed in endothelial cells lining lymphatic vessels. .

Applications

WB

Field of Research

Cardiovascular, Vasculature

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS) . May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

35213 MW

Observed Molecular Weight

43 kDa

Gene Name Synonym

Lymphatic vessel endothelial hyaluronic acid receptor 1

Subcellular Location

Membrane ; Single-pass type I membrane protein . Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand- dependent internalization and recycling at the cell surface.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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