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Anti-JAK1 Rabbit Monoclonal Antibody

Boster Bio Anti-JAK1 Rabbit Monoclonal Antibody catalog # M00330-1. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cytochrome b-245 heavy chain;1.-.-.-; CGD91-phox; Cytochrome b (558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome; CYBB; NOX2

Gene Name

JAK1

Gene ID

3716

UniProt

P23458

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human JAK1

Clonality

Monoclonal

Clone

Clone: 18J08

Tissue Specificity

Detected in neutrophils (at protein level) . .

Applications

WB

Field of Research

Adaptive Immunity, Cancer, Cancer Metabolism, Immunology, Metabolism, T Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H (+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

65336 MW

Observed Molecular Weight

133 kDa

Gene Name Synonym

Cytochrome b-245 heavy chain

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Name

P2X purinoceptor 1

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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