Anti-CD209 Rabbit Monoclonal Antibody
Boster Bio Anti-CD209 Rabbit Monoclonal Antibody catalog # M01025-3. Tested in WB application. This antibody reacts with Human.
Product Specifications
Synonyms
Heat shock cognate 71 kDa protein; Heat shock 70 kDa protein 8; Lipopolysaccharide-associated protein 1; LAP-1; LPS-associated protein 1; HSPA8; HSC70, HSP73, HSPA10
Gene Name
CD209
Gene ID
30835
UniProt
Q9NNX6
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human CD209
Clonality
Monoclonal
Clone
Clone: 17C54
Tissue Specificity
Ubiquitous. .
Applications
WB
Field of Research
Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
70898 MW
Observed Molecular Weight
224-300 kDa
Gene Name Synonym
Heat shock cognate 71 kDa protein
Subcellular Location
Cytoplasm. Melanosome. Nucleus, nucleolus. Cell membrane. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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